Research assistant pinheiro lab mfx fulltime Jobs in Vienna

The Campbell laboratory at CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, is recruiting a highly motivated Technical Assistant to join an international team of scientists working in the field of mucosal immunology / microbiome research.

Our team is looking for a passionate scientist to join as Technical Assistant to support our ongoing projects by maintaining our Special Pathogen-Free (SPF) and germ-free (GF) mouse colonies and assisting with ex vivo and in vivo experiments.

The successful candidate will become an expert in genetic mouse models, infection models and GF animal husbandry. They will also receive the appropriate training to isolate intestinal immune cells and prepare samples for microbiome sequence. In addition, the new group member will participate of individual and group meetings to discuss project directions and career development.

Your Profile

• Degree in life sciences (B.Sc., M.Sc., Mag., DI)
• Eager to join a young team and be trained in new techniques
• Qualified laboratory experience in molecular and cellular biology or immunology
• Experience with mouse handling (FELASA certification or similar is desired, but not required)
• Experience with basic molecular biology (e.g. genotyping PCR, DNA and RNA isolation)
• Basic experience with flow cytometry
• Excellent written and oral communication skills in English
• High accuracy, reliability and independence, able to work seamlessly in a team

Your Tasks

The Campbell Lab

The Campbell lab investigates how metabolic cues affect the differentiation and function of T cells. Our studies focus on the intestinal mucosa, where T cells are exposed to a myriad of microbial metabolites and dietary nutrients. We also want to understand how changes in organismal metabolism that occur as a consequence of gastrointestinal infections impact immune responses.

Our group uses gnotobiotic husbandry, engineered bacterial strains, metabolomics and experimental infection to identify novel mechanisms contributing to the regulation of T cell function in physiological settings.

The Principal Investigator

Clarissa Campbell joined CeMM as a principal investigator in July 2021. She studied biology with a minor in genetics at the Federal University of Rio de Janeiro (UFRJ) and subsequently earned a master’s degree from the Oswaldo Cruz Foundation (FIOCRUZ), investigating how bacterial molecules exert immunomodulatory effects on mammalian cells via nuclear receptors, a topic she would continue to explore throughout her career. She joined the Tri-Institutional Immunology and Microbial Pathogenesis Program at Weill Cornell Medical College in New York as a graduate student where she specialized in mucosal immunology and regulatory T (Treg) cell biology. After obtaining her PhD, Clarissa Campbell remained under the mentorship of Dr. Alexander Rudensky at Memorial Sloan Kettering Cancer Center to continue her work on host-commensal interactions and pursue broader scientific questions bridging the fields of immunology and metabolism. Her research has characterized a circuit whereby microbial metabolites including short-chain fatty acids and secondary bile acids facilitate the differentiation of peripherally induced Treg cells, which in turn suppress immune responses to colonization and preserve a niche for a group of intestinal bacteria. More recently, she found that a bile acid sensing nuclear receptor contributes to the cell-intrinsic responsiveness of effector T cells to fasting. Her lab is interested in investigating how changes in microbial and organismal metabolism contribute to regulating immune-cell function. She is the recipient of the 2023 FEBS excellence award and is part of the FWF SFB HIT- HDAC modulation in T cells (2023) and the FWF Cluster of Excellence Microbes for the planet (2023).

About the Institute

CeMM is an international research institute of the Austrian Academy of Sciences and a founding member of EU-LIFE. The mission of CeMM, the Research Center for Molecular Medicine of the Austrian Academy of Sciences is to achieve maximum scientific innovation in molecular medicine to improve healthcare. At CeMM, an international and creative team of scientists and medical doctors pursues free-minded basic life science research in a large and vibrant hospital environment of outstanding medical tradition and practice. At CeMM, an international and creative team of scientists and medical doctors pursues free-minded basic life science research in a large and vibrant hospital environment of outstanding medical tradition and practice. CeMM’s research is based on post-genomic technologies and focuses on societally important diseases, such as immune disorders and infections, cancer, aging and metabolic disorders. CeMM operates in a unique mode of super- cooperation, connecting biology with medicine, experiments with computation, discovery with translation, and science with society and the arts. CeMM discovers and develops technologies to explore human biology with the purpose of defeating disease at its roots. Because Science is our Medicine! CeMM trains a modern blend of biomedical scientists and is located at the campus of the General Hospital and the Medical University of Vienna. CeMM is a proud recipient of the HR Excellence in Research Award (HRS4R). This award indicates that CeMM takes care of the well-being of its employees, that the recruitment process is open, fair, and transparent, and that CeMM offers professional appraisals and career development procedures. More than 150 people from 49 nationalities are working at CeMM. The institute promotes equal opportunity and harbours a mix of different talents, backgrounds, competences, and interests.

We offer

Additional information

City Vienna

Position type Full-time employee

Start of work 01.11.2023

Responsible Memo Mokhles